Matteo Arnaldi enters the Cagliari semi-finals as the higher-ranked player at world No. 103, seeking to build on a mixed recent record that includes wins over Juan Manuel Cerundolo and Franco Arnaboldi. The Italian clay-courter has struggled against top opposition lately, losing to Dušan Lajović, Quentin Halys and Cameron Garin in his last five matches. Arnaldi holds no head-to-head history against Gabriele Cadenasso and faces Pinnacle odds of 1.67 as the favourite in this all-Italian semi-final clash on home soil.

Gabriele Cadenasso, ranked 232nd globally, qualified for the Cagliari semi-finals with recent wins against Matteo Bellucci and Lorenzo Carboni on clay. The Italian player's form remains inconsistent, having also suffered losses to Jelle Vasami and Hugo Gaston in his last five outings. This marks Cadenasso's first head-to-head meeting with Arnaldi, and he enters as the underdog at Pinnacle odds of 2.31 in a semi-final matchup against a significantly higher-ranked opponent.